Troponin C Totally Explained

Everything about Troponin C totally explained

Troponin C is a part of the troponin complex. It contains four calcium-binding EF hands. It contains an N lobe and a C lobe. The C lobe serves a structural purpose and binds to the N domain of TnI. The C lobe can bind either Ca2+ or Mg2+. The N lobe, which binds only Ca2+, is the regulatory lobe and binds to the C domain of TnI after calcium binding.
The tissue specific subtypes are:

Slow troponin C, TNNC1 (3p21.3-p14.3, )
Fast troponin C, TNNC2 (20q12-q13.11,

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